Neural Tube Defects

Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)

Also Known As:

Exencephaly; Diastematomyelia; Iniencephaly; Neural Tube Defect; Craniorachischisis; Acrania; Developmental Neural Tube Defects; Neural Tube Developmental Defects; Neuroenteric Cyst; Occult Spinal Dysraphism; Occult Spinal Dysraphism Sequence; Tethered Spinal Cord Syndrome; Acranias; Craniorachischises; Cyst, Neurenteric; Cyst, Neuroenteric; Cysts, Neurenteric; Cysts, Neuroenteric; Defect, Neural Tube; Defects, Neural Tube; Diastematomyelias; Dysraphism, Occult Spinal; Dysraphisms, Occult Spinal; Exencephalies; Iniencephalies; Myelodysplasia, Spinal Cord; Myelodysplasias, Spinal Cord; Neurenteric Cysts; Neuroenteric Cysts; Occult Spinal Dysraphisms; Spinal Cord Myelodysplasias; Spinal Dysraphism, Occult; Spinal Dysraphisms, Occult; Tethered Cord Syndromes; Developmental Defects, Neural Tube; Neurenteric Cyst; Spinal Cord Myelodysplasia; Tethered Cord Syndrome

Nervous System Diseases: 14178
- Nervous System Malformations: 35
  - Neural Tube Defects: 4299
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Congenital Abnormalities: 25723
  - Nervous System Malformations: 35
    - Neural Tube Defects: 4299

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